
Alice Matthews, Ph.D. RDCS
Cardiac Specialist & AI Researcher
ARDMS #204043 | Pediatric Echo Specialist | Patient Advocate
Bridging advanced cardiac imaging with artificial intelligence to improve healthcare outcomes for vulnerable populations.
Clinical Research AI & Leadership
Clinical Research AI
Clinical-domain expertise guiding AI systems for cardiovascular diagnostics, clinical trial data extraction, medical knowledge retrieval, and safer translation of research workflows into care settings.
Pediatric & Congenital Cardiac Imaging
Specialized training in one of only two CAAHEP-accredited pediatric echocardiography programs in the U.S., with advanced neonatal, NICU, and congenital pathology experience.
Research Leadership & Advocacy
Research and service focused on vulnerable populations, Down syndrome cardiovascular health, medical education, patient advocacy, and responsible use of AI in healthcare.
About
Dr. Alice Matthews is an ARDMS-certified cardiac sonographer (RDCS #204043) and Neuroscience Ph.D. graduate who bridges advanced cardiac imaging expertise with cutting-edge artificial intelligence research. With over a decade of clinical experience spanning adult, pediatric, and special populations, she brings a rare combination of hands-on clinical mastery and sophisticated research capabilities to healthcare AI development.
Her specialized training sets her apart in the field. Alice completed one of only two CAAHEP-accredited pediatric echocardiography programs in the United States, mastering advanced neonatal and congenital cardiac imaging techniques through intensive NICU scanning and complex pathology case studies. This elite specialization reflects her commitment to serving the most vulnerable patients, a theme that runs throughout her career from her work as a Patient Advocate at Children's Specialty Center of Nevada to her groundbreaking Ph.D. research on cardiac function in adults with Down syndrome.
Her doctoral dissertation, "Echocardiographic Evaluation of Cardiac Structure, Function, and Ventricular-Arterial Coupling in Adults with Down Syndrome," exemplifies her dedication to underserved populations. This research addresses critical gaps in cardiovascular care for individuals with intellectual disabilities, investigating how exercise interventions affect cardiac health in a population that faces unique healthcare challenges. Her work has been published in leading journals including the Journal of Intellectual Disability Research and International Journal of Environmental Research and Public Health.
Beyond the clinic and laboratory, Alice is a fierce advocate for those who cannot protect themselves. She has served as a medical volunteer for Special Olympics Nevada, contributed to the Medical Down Syndrome Conference, and actively fundraises for GiGi's Playhouse, efforts that have directly enhanced therapeutic and educational programs for children with Down syndrome and their families. This advocacy work isn't peripheral to her research; it's central to her mission of ensuring that advanced medical technologies and AI-driven healthcare innovations reach the populations that need them most.
At DeepNeuro.AI, Alice leverages her clinical expertise and technical skills to advance machine learning applications in cardiovascular diagnostics. Her recent publication on benchmarking large language models for automated clinical trial data extraction demonstrates her ability to translate practical healthcare challenges into innovative AI solutions. She understands the nuances of clinical data because she has collected thousands of echocardiograms herself, a perspective that informs more thoughtful, clinically relevant AI development.
When she's not in the lab or clinic, you'll likely find Alice on roller skates. An avid and highly competitive roller skater, she brings the same focus, precision, and fearlessness to the rink that she applies to her research and patient advocacy work. Whether navigating complex cardiac pathology, developing AI systems, or perfecting her skating technique, Alice approaches every challenge with determination and grace.
Expertise
Pediatric Cardiac Imaging
CAAHEP-accredited pediatric echocardiography specialist, one of only two programs in the U.S. Expert in neonatal and congenital cardiac imaging with advanced training in complex cardiovascular pathology.
Clinical Cardiac Research
Over 10 years of clinical experience with expertise in adult and pediatric echocardiography, stress echo, TEE, and advanced Doppler techniques across diverse patient populations.
Clinical Research AI
Applying large language models and machine learning to clinical trial data extraction, cardiovascular diagnostics, medical knowledge retrieval, and healthcare AI applications for improved patient outcomes.
Advocacy & Special Populations
Dedicated advocate for vulnerable populations with extensive research on cardiac function in adults with Down syndrome and volunteer work with Special Olympics Nevada and GiGi's Playhouse.
Medical Education
Teaching and curriculum development in cardiac imaging and sonography, with experience as an Alteryx SparkED Faculty Advisor and guest lecturer on AI applications in medical education.
Clinical Research Methods
Expertise in clinical study design, data collection methodologies, and statistical analysis, with CITI-certified research ethics training across multiple institutions.
Medical AI/ML Leadership
Development, validation, and domain review of AI tools for clinical diagnostics, including LLM benchmarking, cardiology embeddings, and multimodal RAG systems for medical knowledge retrieval.
Selected Publications
Benchmarking multiple large language models for automated clinical trial data extraction in aging research
Young RJ, Matthews A, Poston B
Measurement protocols and determinants of peak oxygen consumption in adults with Down syndrome: a systematic review
Hilgenkamp TIM, Beck VDY, Azar F, Maloy-Robertson M, Matthews A, et al.
Cardiac structure and function in adults with Down syndrome
Azar FM, Beck VDY, Matthews AM, Forsha DE, Hilgenkamp TIM
Beyond the Lab
When she's not advancing cardiac imaging research or advocating for special populations, Alice is a highly competitive roller skater. She brings the same precision, focus, and fearlessness to the rink that defines her approach to complex clinical challenges and AI innovation.
Medical RAG System
Alice's private AI-powered cardiac ultrasound knowledge base. Multimodal search across medical textbooks with page-accurate citations and inline image display.
Private access • Apply for access below
Let's Collaborate
Interested in cardiac imaging research, AI applications in healthcare, or advocacy for special populations?